PUGO held a 2 day meeting in Scotland prior to the IASP 12th World Congress on Pain to consider the past, present and future of urogenital pain. The aim was to outline current practice and have a look at what the future may hold. Speakers from North America and Europe gave invited lectures, and interactive sessions with all meeting attendees were interspersed throughout the proceedings leading to very lively discussions
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More: http://www.newswise.com/articles/view/543710/Tony Buffington from Columbus, Ohio opened the second day of the meeting. His presentation covered comorbidities, vulnerability factors, and familial aggregation data. Specifically he discussed variable combinations of idiopathic chronic pain syndromes including bladder pain syndrome, fibromyalgia, irritable bowel syndrome, chronic pelvic pain syndrome, chronic fatigue syndrome, as well as affective disorders such as post traumatic stress disorder, panic disorder, anxiety and depression. These are commonly seen together in patients. They comprise MUS or medically unexplained symptoms, and may affect up to 1/3rd of people seeking medical care. One candidate underlying disorder is sensitization of the central stress response system and an imbalance in its output in response to stressors. Enhanced sensitivity may result from variable combinations of familial (genetic and environmental) factors. He hypothesizes that sensitization creates a greater vulnerability to life stressors, putting certain individuals at greater risk of developing disorders characterized by pain and discomfort.
