Epidemiology. 2004 Jan;15(1):93-9.
Prostatitis as a risk factor for prostate cancer.
Roberts RO, Bergstralh EJ, Bass SE, Lieber MM, Jacobsen SJ.
Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, Minnesota 55905, USA.
BACKGROUND: The association of infection or inflammation of the prostate with prostate cancer has been suggested but not established. This study was undertaken to investigate this association.
METHODS: Cases were Olmsted County, Minnesota, residents with histologically proven prostate cancer diagnosed between January 1980 and December 1996. Cases (n = 409) were each matched to 2 control subjects (n = 803) on age at diagnosis of prostate cancer, residency in Olmsted County, and duration of the community medical record. The medical record of each subject was reviewed for a history of acute or chronic bacterial prostatitis or chronic pelvic pain syndrome (inflammatory type).
RESULTS: The relative odds of prostate cancer were elevated in men with history of any type of prostatitis (odds ratio [OR] = 1.7; 95% confidence interval [CI] = 1.1-2.6) or acute prostatitis (2.5; 1.3-4.7). The mean time from most recent episode of acute prostatitis to the diagnosis of prostate cancer was 12.2 years. After exclusion of men with acute prostatitis 2 years before the index date, the relationship was somewhat reduced (1.9; 0.9-3.8). Chronic bacterial prostatitis was more weakly associated with prostate cancer (1.6; 0.8-3.1), whereas chronic pelvic pain syndrome was not associated at all (0.9; 0.4-1.8).
CONCLUSIONS: Infection in the form of acute or chronic bacterial prostatitis may be associated with prostate cancer. However, our data do not provide compelling evidence to support this. As a result of the limitations of current methods of assessing chronic prostatitis, biochemical or tissue markers of infection or inflammation of the prostate may help clarify their role in the pathogenesis of prostate cancer.
Good News! CPPS NOT associated with Prostate Cancer
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webslave
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Good News! CPPS NOT associated with Prostate Cancer
Good News! The great ProstaQ is BACK at last! You must try it.
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MastCells
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Re: Good News! CPPS NOT associated with Prostate Cancer
Bad news for Ronny Wheeler. Good news for chronic prostatitis / chronic pelvic pain syndrome patients everywhere. It's nice to know that chronic prostatitis / chronic pelvic pain syndrome isn't associated with prostate cancer. As if we don't have enough to worry about with overcoming our pain and discomfort!
This is not medical advice. Please consult your physician.
