Diet and CPPS

Male pelvic pain, prostatitis, IC
rcalab

Diet and CPPS

Post by rcalab »

:sad:

I have chronic prostatitis / chronic pelvic pain syndrome and I am currently dumbfounded as to why certain foods cause flair-ups. I have been making progress with my acupuncture treatments, yoga, avoiding unnecessary muscle strains (this due to flair-ups that have resulted from weight-training), and a strict diet. For the past two weeks, I've felt particularly strong (pretty much asymptomatic). Yet last night I had 3 egg whites, which resulted in a fairly significant flair up; I could not fall asleep due to the discomfort. I had egg-whites the night before with no problem, and I kept everything else constant. No other differences in what I ate or my activities. I did have a reaction to eggs about a month and a half ago, but felt strong enough now that I thought I would be ok. I did have a food allergy test done, and it came up negative. I have had similar reactions to cheese, and, of course spicy foods and caffeine, which I avoid. What I do not understand, and what has not been answered (or hardly addressed) in all of the reading I've done on this condition is: IF THIS IS A NEUROMUSCULAR ISSUE REGARDING THE PELVIC FLOOR, HOW/WHY WOULD CERTAIN FOODS CAUSE THESE TYPE OF REACTIONS???? I do not understand what possible connection there could be between the Pelvic floor and the kinds of foods one eats. I read Dr. Wise's book, and I did not come across an answer to this question.

Your responses are greatly appreciated.
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Post by webslave »

Actually, this issue has been adressed many times in these forums. Mast cells degranulate when exposed to allergens (for you, eggs are an allergen, and BTW eggs are one of the most common allergens). chronic prostatitis / chronic pelvic pain syndrome involves, inter alia, a proliferation of mast cells in the lower gentito-urinary tract. So, of course, if you ingest allergens or mast cell provocateurs, you will have symptoms in any area of the body where mast cells are numerous and are exposed to these ingested products or their metabolites.
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Post by rcalab »

I did do some more reading on Mast cells and diet. It seems that there is no clear way to stop Mast cell production, which apparently is a major factor that can cause flair-ups, with the triggers being certain foods one eats or exercise that involves weighttraing, etc. Can anyone answer why someone with chronic prostatitis / chronic pelvic pain syndrome would be more susceptable to Mast Cell production? My quandry in particular is that I have been ok (minimal symptoms) with acupuncture treatment, yet the underlying issue (going on 6 months now) still remains. My diet is significantly restricted, I can't work out in any strenuous capacity (exept yoga), and even ejaculation cause pelvic pain after the fact. With an active lifestyle, this conditon (as so many of you know) is quite debilitating. Is it possible that as the condition continues to dissipate, this susceptability to certain foods, excercise, etc., with just go away. Has anyone had this experience???

What do you think about hydroxyzine? I've read that some people swear by its effectiveness in blocking histamines, and reducing the effects of mast cell production.

Can anyone offer another alternative that has helped with increasing one's tolerance to certain foods, or enabling one to excercise again with minimal discomfort???

Thanks for your comments and help! I wish I could take a "holiday" from this condition, but my discomfort is making this quite difficult.

Happy holidays everyone!
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Post by webslave »

rcalab wrote:Can anyone answer why someone with chronic prostatitis / chronic pelvic pain syndrome would be more susceptable to Mast Cell production?
The theory du jour states that hormones/neuropeptides produced by hyperstimulated nerves (e.g. the nerves involved in pelvic muscle spasm) trigger proliferation. Other causes are diseases like mastocytosis, although that has not been formally linked to CPPS.
Is it possible that as the condition continues to dissipate, this susceptability to certain foods, excercise, etc., with just go away. Has anyone had this experience???
My experience is that avoidance of trigger foods is key, and usage of 150mg Zantac nightly (do not use generic, use Zantac itself, I find).
What do you think about hydroxyzine? I've read that some people swear by its effectiveness in blocking histamines, and reducing the effects of mast cell production.
I had problems with it (see antihistamine forum), but some people can tolerate it well.
Can anyone offer another alternative that has helped with increasing one's tolerance to certain foods, or enabling one to excercise again with minimal discomfort???
Quercetin, Zantac, big doses of Esterized Vitamin C, gentle exercise like walking. If you are execise intolerant, you may have the common CFS component of CPPS/PM going on.
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Post by rcalab »

Thanks for all your help, but still have a few questions based on your last reply:

1) It seems, at least by the latest theory, that muscle spasms might be the root cause of the problem, giving rise to mast cells, which then degranulate (release chemicals like histamines) which then cause the kind of irritation and pain we all seem to experience. If that's the case, do you think that the treatment advocated by Dr. Wise makes sense? That is, myofascial/trigger point release where the muscles in the pelvic area are worked on directly? It seems that the results from this are mixed, or inconclusive. I did, howver, really enjoy Dr. Wise's book.

Incidently, one thing I can recommend without qualification (and no side effects) is acupuncture. I found an acupuncturist who is a medical doctor. Everytime I've gone to him in pain (excrutiating at times), I've walked out of there essentially pain free. The treatment lasts, but I seem to have all of these triggers that short circuit the acupuncture. He's in New York, if you want the number.

Thanks again for your help.
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Post by webslave »

rcalab wrote:do you think that the treatment advocated by Dr. Wise makes sense? That is, myofascial/trigger point release where the muscles in the pelvic area are worked on directly? It seems that the results from this are mixed, or inconclusive.
Anecdotal evidence strongly supports Wise and Anderson's work, as well as that by Weiss and many others in this field, like Rhonda Kotarinos etc. However, properly controlled and reviewed studies are lacking. This deficiency is currently being addressed. Wise and Anderson are now funded by the NIH/NIDDK to study the Stanford/Wise-Anderson Protocol.
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Post by rcalab »

Hi,

I wanted to follow up on something else. As I mentioned to you in my first message, I had an allergy test for food that came up negative. If certain foods are allergens for me, I can see, by what you said, why I would react to them, but according to the test, I am not allergic to any foods. Can the mast cells be effected by the food even though I am not allergic, and why would this happen? Do you know of a good source, other than the forum, to look into this issue?

Thanks again for all your help; it's much appreciated.

rob
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Post by webslave »

For reasons which we do not yet fully understand, skin prick testing with food allergens is less reliable than with some other allergens such as dust and pollens, so false negative reactions can occur. This is well known. Complicating matters is that some of the "allergy" reactions are actually delayed hypersensitivity reactions, not always involving the classic IgE, but other elements of the immune system, like IgG. It really is an extremely complex area of study.

For our practical purposes, food allergen identification is still best performed with an exclusion diet.

An excellent reference here:
http://www.amazon.com/exec/obidos/ASIN/ ... I'm/cp58-20
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