supplements

kafka · Post by **kafka** » Thu Oct 31, 2002 6:35 pm

Some time ago, Dr. Dimitrakov mentioned a German product being used for neuropathy; what was that? Also, at the suggestion of my pain M.D. I've started to use alpha lipoic acid and taurine for nerve pain; thoughts? JP

J Dimitrakov · Post by **J Dimitrakov** » Thu Oct 31, 2002 7:05 pm

The name of the product is "Milgamma N". Ingedients: lipid-soluble vitamin B1 (benfothiamine), vitamin B6 and vitamin B12.

kafka · Post by **kafka** » Thu Oct 31, 2002 10:07 pm

Dr. Dimitrakov, do you have any thoughts/experience as to the efficacy of Milgamma N or other supplements, including alpha lipoic acid and taurine, with respect to CPPS? Thank you. JP

J Dimitrakov · Post by **J Dimitrakov** » Thu Oct 31, 2002 10:30 pm

kafka wrote:Dr. Dimitrakov, do you have any thoughts/experience as to the efficacy of Milgamma N or other supplements, including alpha lipoic acid and taurine, with respect to CPPS? Thank you. JP

=====Milgamma N has been quite well-tolerated by all patients that have taken it so far and has been effective for neuropathic pain control. I have no experience with alpha-lipoic acid or taurine but theoretically they seem to make sense.

dshoskes · Post by **dshoskes** » Sat Nov 02, 2002 11:27 am

Any sense of how many of your patients have taken it, how many it helped and what improvement in the NIH-CPSI was seen in those patients it helped? Did they take it as first line therapy or only after other treatments (Elavil, Neurontin) failed?

Milgamma N has been quite well-tolerated by all patients that have taken it so far and has been effective for neuropathic pain control. I have no experience with alpha-lipoic acid or taurine but theoretically they seem to make sense.

J Dimitrakov · Post by **J Dimitrakov** » Sat Nov 02, 2002 12:56 pm

dshoskes wrote:Any sense of how many of your patients have taken it

So far, about 50 patients

how many it helped

About 70 %

and what improvement in the NIH-CPSI was seen in those patients it helped?

Mainly in th pain-related domain

Did they take it as first line therapy or only after other treatments (Elavil, Neurontin) failed?

They took it after other treatments had failed.

Post by **webslave** » Sat Nov 02, 2002 3:10 pm

This medication sounds like something we should know more about! :D

J Dimitrakov · Post by **J Dimitrakov** » Sat Nov 02, 2002 4:22 pm

webmaster wrote:This medication sounds like something we should know more about! :D

It will be undergoing evaluation in a double-blind placebo-controlled study soon. The problem is the company is not interested so it will be a bit difficult to fund the study.

jp · Post by jp » Mon Nov 04, 2002 11:50 pm

Is there something special about this supplement that makes it better than plain old B vitamins? Could a patient get the same effect from simply taking the subject B vitamins? Thanks. JP

J Dimitrakov · Post by **J Dimitrakov** » Tue Nov 05, 2002 12:57 am

jp wrote:Is there something special about this supplement that makes it better than plain old B vitamins?
====It is lipid-soluble vitamin B unlike the plain old vitamin B combo which is water-soluble. Since nerves are rich in lipids and lipids are soluble in lipids, the lipid formulation has greater efficacy than the water-soluble one.

Could a patient get the same effect from simply taking the subject B vitamins? Thanks. JP

====Maybe. But you need to take it for a longer time and probably at higher doses.

Rick · Post by **Rick** » Fri Nov 15, 2002 4:50 am

Is this medication available? In the US?

J Dimitrakov · Post by **J Dimitrakov** » Sat Nov 16, 2002 2:47 am

Rick wrote:Is this medication available? In the US?

No, it's not available in the US.

Rick · Post by **Rick** » Tue Nov 19, 2002 9:41 pm

Dr. D in your opinion what supplement's would be similar to Milgamma-N? You also mentioned awhile back something about Tribulis for dialated seminal vesicles could you elaborate on that a little more please. I have been diagnosed with dialated seminal vesicles + chronic prostatitis / chronic pelvic pain syndrome and I also remember you mentioning that that this could cause back pain aroung the kidney area. This has been a problem now for 14 months and I am desperatley looking for something to help especially with the back problem. Everyday same thing never gets any better no matter what I try Yoga, Stretching, Whirlpool, nothing.
Apologize for the long post will be more brief in the future. :?

J Dimitrakov · Post by **J Dimitrakov** » Tue Nov 19, 2002 9:59 pm

Rick wrote:Dr. D in your opinion what supplement's would be similar to Milgamma-N?

Well, it's not the simple combo of the vitamins inside (vit B1+B6+B12) but rather the fact that you get the lipid-soluble formulation (as compared to OTC formulations which are water-soluble). Since lipids dissolve well in lipids, this formulation has been shown to penetrate nerves better than the water-based one (sincenerves are rich in lipids)

You also mentioned awhile back something about Tribulis for dialated seminal vesicles could you elaborate on that a little more please.

Tribulus has properties similar to natural testosterone and since smooth muscle contractions in the prostate and seminal vesicles have been shown to be under testosterone control, it probably stimulates contraction in this way.

I have been diagnosed with dialated seminal vesicles + chronic prostatitis / chronic pelvic pain syndrome and I also remember you mentioning that that this could cause back pain aroung the kidney area. This has been a problem now for 14 months and I am desperatley looking for something to help especially with the back problem. Everyday same thing never gets any better no matter what I try Yoga, Stretching, Whirlpool, nothing.

Yoga and stretching can actually make it worse.

UCPPS - Prostatitis, Interstitial Cystitis Forum

UCPPS - Prostatitis, Interstitial Cystitis Forum

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