Any information on intraprostatic injection??

[craig]

I would love to hear some success stories concerning this procedure. If anyone out there can give some input on the issue it would be greatly helpful

craig

[webslave]

If you are in the US, you can contact Dr Bahn, details here and he can refer you to some successful patients, perhaps.

[Mike]

I know someone that had Intraprostatic Injection that lives in my area and it has made him *worse* than previous to getting it he told me.

Mike

[J Dimitrakov]

I know someone that had Intraprostatic Injection that lives in my area and it has made him *worse* than previous to getting it he told me.

Mike

I have seen at least 10 people so far that have been made worse by the injections and not a single one who has had sustained improvement beyond the period around the injections

[craig]

so did this person goto Dr. Bahn or someone else?? What kind of symptoms made him worse? Could you give me any details on this topic?


craig

[craig]

Dr. D could you give me any information on the people who have treated with this procedure and have had bad results? Is there any patient I could possibly talk to before I have this procedure done? ANy information would be greatly appreciated

Dr. craig siegel

[J Dimitrakov]

Dr. D could you give me any information on the people who have treated with this procedure and have had bad results? Is there any patient I could possibly talk to before I have this procedure done? ANy information would be greatly appreciated

Dr. craig siegel

Dear Dr. Siegel:

I have seen three English-speaking people (1-American, 1-Norwegian and 1 Italian) who had undergone the procedure. I am not sure they would be willing to discuss it but I will ask them. I have 10 more Bulgarian patients but it would not be possible to communicate with them over the internet since they do not speak English. The Italian patient lost sensitivity of his penis. The other two had increase in pain following the procedure. None of them had been to Dr. Bahn. The urologic literature is replete with reports on the intraprostatic injection technique so, I would suggest you search PubMed for "prostatitis AND injection AND antibiotics" and you get 23 hits. Remember none of the studies is a RCT, they are not well controlled and the definition of prostatitis is "vague". If you are having difficulties, please let me know and I can e-mail you any study you are interested in from my personal prostatitis library.

[craig]

thanks for the information. I will do some more research on the subject. If you could possibly find out if I could toalk to those patients it would be greatly appreciated


dr craig

[alan1]

My recent clinical history is summarized below:
In 1999 I experienced a urethritis after having sex with a new partner.
The diagnosis was: unidentified pathogen. I was given a 7 day course of doxycycline, I got somewhat better but had a relapse.
After several 10 day courses of erythromycin or doxycycline with no improvement over 6 months, I had an RPG ( dilation of the urethra)done while administering Rocephine by IV, as a result I cleared up entirely of all my symptoms.
I had a relapse shortly after that, I believe that I was reinfected, although my partner had gone on a course of antibiotics and all her cultures turned out negative.
Then I went through 3 months of erythromycin plus doxycycline plus diflucan and cleared up again. My girlfriend went through the same regimen and we thought that she would be cleared as well, instead I got infected again.
I went again on erythromycin plus doxycycline for 10 months with no improvement.A second RPG failed to treat my symptoms.
Switched over to Biaxin (clarithromycin) plus doxycycline and I had some relief.
I was off antibiotics for 9 days and was cultured for Vb1 vb2 vb3 plus yeasts and mycoplasma. Only Candida showed a positive result.
At this point I had a CT scan, an ultrasound and an MRI done.
The CT showed bilateral "stones".
The MRI showed diffused inflammation of the tissue surrounding the prostate.
In October 2002 (over 2 years from the beginning of this ordeal) it was established that I was not a candidate for microwave therapy, therefore I looked for alternative therapies available on the WEB.
I came across Dr. Guercini's approach to this disease.
He claims that cultures normally done for urethritis and prostatitis often results in false negatives. He, therefore, advocates PCR testing. An added advantage of PCR testing is that it can be done while undergoing antibiotic therapy.
He used for me a cocktail of the following antibiotics:
Cipro
doxycycline
biaxin
diflucan
cortisone
the infiltrations were done using an ultrasound during the procedure in order to guide the needle properly. I watched the images during the procedures and I observed the "stones" actually breaking into many little pieces on the screen, as the antibiotics diffused throughout the prostate gland.
Samples of my sperm and urine were sent to a lab for PCR testing.
The pain during the procedure was minimal, the bleeding after the procedure could only be observed in the sperm for three days following each procedure.
I was subjected to three infiltrations;
after 24 hours after the first infiltration I began to feel better.
The suffused discomfort in my pelvis and lower back was almost entirely gone. Though, after a few days I developed a urethritis.

In the meantime the results of my PCR test had come back from the lab and showed that I was infected with some micro-organisms that were never detected in the previous tests. Antibiotics I'm were prescribed for the UTI which got a lot better.
I still have peripheral pain occasionally (Reiter's disease?), a minimal clear discharge from the penis and occasional itching of the urethra, but my libido and erections have been restored to almost the levels that were normal prior to this infection (1999).

I believe that I might be still infected with some other micro-organism. Perhaps a fungus or a yeasts as a result of 3 years on antibiotics.
But I am definitely better, I will post updates as I (hopefully) heal completely.
alan

[webslave]

Thank you very much for posting your history! I feel it only fair to tell the readers that I do know who you are (a real person), but I will not disclose your identity for privacy reasons.

You seem convinced that you were infected, but what about the effect of the dexamethasone in the injections? With all the negative cultures, isn't it more likely that this is what helped you?

[Ralph]

Alan, you made an interesting post. Prostatitis may be caused by an infection, but something else must be going on. The symptoms are too varied and diffuse. An autoimmune reaction may occur after the initial infection. Just a thought. I would also be surprised if prostatic samples were always sterile. I'm not surprised bacteria were found. That doesn't mean that caused your problem.How many asymptomatic men have bacteria in the prostate? No one knows because we don't do random samples on asymptomatic men. I would venture a guess that many have foci of bacteria in the prostate and don't have CP.

[alan1]

In my case I am absolutely certain that I was infected. Each time that I got infected the infection manifested itself with a urethritis that began almost exactly 48 hours after sex. Another indication of the fact that mine is an infection is that over the three years of my ordeal I could tell that I was reinfecting my urethra periodically even without having sex. What I mean is that every 7 to 10 days I would re-experience itching of the urethra. Also I could always during these three years, observe a clear but minimal discharge from the penis. The discharge is not cleared yet entirely, that's why I believe now that a fungus or a yeast may be responsible. Finally, PCR testing last october confirmed that I was in fact infected with three microorganisms.

The phisician that treated me is dr. Guercini in Rome, Italy. The Lab that did the PCR testing was arranged by him.

As for the question about the role that cortisone played in my improvement, I cannot comment on it.

I will keep you posted of my improvement or worsening conditions. I have submitted a new set of samples for PCR testing and I ought to have results in a week or two.
alan

[webslave]

I will keep you posted of my improvement or worsening conditions.

Thanks, A. We will follow your case with a lot of interest!

[Ralph]

Dr. D recently cited an article from the Journal of Urology 2003 169(2):584-588 in the usernet newsgroup (google) which found similar bacteria cultured from prostatic biopsies performed on men with and without CP. In other words, bacteria are found in the prostate of normal (asymptomatic) patients. Conclusion: bacteria probably do not play a role in the symptoms associated with CPPS. No one knows what is really going on with this condition. A lot of speculation all around. Funding more research is the only answer. As they said in the movie The Right Stuff; "no bucks, no Buck Rogers".

[gunde]

I've had most cp symptoms (except for loss of libido) and theyve not been mild. Still there's never been any indication of bacteria and I personally dont think I suffer from bacterial prostatitis.