I can't fully agree here. The muscular path isn't the solution for everyone. Pain management with a responsible, multi-disciplinary approach - including meds - has been helpful to me over the long term. Cure, no, but it maintains a quality of life after other choices have been investigated.webslave wrote:Yet more evidence that pain meds, specifically opioids, are a dead end. They are useful only in short bursts, but if you rely on them for more than that, it becomes self-defeating.Also, I went through the Wise-Anderson clinic in 2005. Of everything I've seen over the years I truly believe those guys have begun to crack this thing. I have nothing but good to say about their program. It hasn't worked for me however because I wasn't disciplined enough and resorted the shortcut of pain meds. Now, even with those meds the pain is breaking through, so I am forced to resume my quest to find some way out.
Hello all! I'm new!
Re: Hello all! I'm new!
I am not a physician. This is not medical advice. Consult your doctor!
Age: 26 Onset Age: 17 Symptoms: Shooting, nerve-like pains throughout the penis, which abruptly hit and leave. Testicular pain, perineum pain, burning/irritative urination, extended pain after ejaculation. Occasionally, some allodynia or ache in the coccyx/sacrum/thigh/buttocks/legs. Diagnosis: Pelvic floor dysfunction, degenerated lumbar disk, and mildly herniated lumbar disk. Helped By: Physical therapy, pain management doctor, hot baths, therapy pool, stretching regimen, breathing exercises, relaxation, distraction. Worsened By: Arousal/ejaculation (worst), constipation, panicking/obsessing, other triggers depend upon current symptoms. Tests/Prior Treatments: Too many antibiotics to count, multiple urine tests (all normal), testicular ultrasound (normal), bladder and renal ultrasound (normal), lumbar and pelvic MRI with and w/o contrast (revealed disk problems), Elavil 25mg (caused retention), Flomax 0.4mg.
Age: 26 Onset Age: 17 Symptoms: Shooting, nerve-like pains throughout the penis, which abruptly hit and leave. Testicular pain, perineum pain, burning/irritative urination, extended pain after ejaculation. Occasionally, some allodynia or ache in the coccyx/sacrum/thigh/buttocks/legs. Diagnosis: Pelvic floor dysfunction, degenerated lumbar disk, and mildly herniated lumbar disk. Helped By: Physical therapy, pain management doctor, hot baths, therapy pool, stretching regimen, breathing exercises, relaxation, distraction. Worsened By: Arousal/ejaculation (worst), constipation, panicking/obsessing, other triggers depend upon current symptoms. Tests/Prior Treatments: Too many antibiotics to count, multiple urine tests (all normal), testicular ultrasound (normal), bladder and renal ultrasound (normal), lumbar and pelvic MRI with and w/o contrast (revealed disk problems), Elavil 25mg (caused retention), Flomax 0.4mg.
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Tramadol, opioids, mast cell degranulation
I've seen several men who have failed to progress at all. Almost all of them were taking opioids on a daily basis.
The facts are that:
A 2010 paper shows that hyperalgesia can be induced by opioids. Another 2010 study posits that Tramadol triggers "an opioid receptor-dependent release of histamine from the mast cells". And there are numerous other suggestive studies.
Be careful.
The facts are that:
- This is a condition in which mast cells are degranulated by neuropeptide activity at the nerve endings in the lower genitourinary tract (see studies by Theoharides).
- Any medication that promotes degranulation will exacerbate the condition.
A 2010 paper shows that hyperalgesia can be induced by opioids. Another 2010 study posits that Tramadol triggers "an opioid receptor-dependent release of histamine from the mast cells". And there are numerous other suggestive studies.
Be careful.
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Re: Hello all! I'm new!
All, just checking in. Wanted to post that I have had zero symptoms in months......this is a success story for those anxious newcomers......when I first visited this group I was severely anxious .....as you can see from my initial posts. Either way......I was able to cure mine through healthy eating, stretching (which I still do on a daily basis) and reduction of stress. I also consciously relax my pelvic floor during orgasm and moment to moment relaxation. Not sure if the fish oil has helped but I take it every day.....call me a fortunate one......either way I am ecstatic that this part of my life is far behind me. Good luck to you all and lower your anxiety!
Age:31 | Onset Age: 31 | Symptoms: minor lower back pain, perineum pain, rectum, testicular....I have to shake and push a lot at the end of urination, but have had to for years. My initial onset was April 3rd 2011. I had major testicle and lower back pain. It has subsided to minor. My biggest problem is pain for days after sex. | Helped By: Eating healthy, hot baths, external PT, therapy, not thinking about it..Any other suggestions? I'm a bit hesitant to do internal PT.... | Worsened By: sex, alcohol, salt intake, stress/anxiety, sitting....biggest flares come on weekends after sex/alcohol and eating wrong....I am now cured as of May 20th or so from relaxation, healthy lifestyle, no stress/anxiety, eating properly, prosta Q, fish oil, external myofascial trigger point massage and TIME. Time heals everybody....Good luck and thank you all!

